Serologic screening of United States blood donors for Babesia microti using an investigational enzyme immunoassay
نویسندگان
چکیده
منابع مشابه
Determination of Babesia microti seroprevalence in blood donor populations using an investigational enzyme immunoassay
BACKGROUND Transfusion-transmitted babesiosis caused by Babesia microti has emerged as a significant risk to the US blood supply. This study estimated the prevalence of B. microti antibodies in blood donors using an investigational enzyme immunoassay (EIA). STUDY DESIGN AND METHODS A peptide-based EIA that detects both immunoglobulin (Ig)G and IgM antibodies to B. microti was developed and va...
متن کاملVertical Transmission of Babesia microti, United States
Babesiosis is usually acquired from a tick bite or through a blood transfusion. We report a case of babesiosis in an infant for whom vertical transmission was suggested by evidence of Babesia spp. antibodies in the heel-stick blood sample and confirmed by detection of Babesia spp. DNA in placenta tissue.
متن کاملScreening for Babesia microti in the U.S. Blood Supply.
BACKGROUND Babesia microti, a tickborne intraerythrocytic parasite that can be transmitted by means of blood transfusion, is responsible for the majority of cases of transfusion-transmitted babesiosis in the United States. However, no licensed test exists for screening for B. microti in donated blood. We assessed data from a large-scale, investigational product-release screening and donor follo...
متن کاملBorrelia burgdorferi Promotes the Establishment of Babesia microti in the Northeastern United States
Babesia microti and Borrelia burgdorferi, the respective causative agents of human babesiosis and Lyme disease, are maintained in their enzootic cycles by the blacklegged tick (Ixodes scapularis) and use the white-footed mouse (Peromyscus leucopus) as primary reservoir host. The geographic range of both pathogens has expanded in the United States, but the spread of babesiosis has lagged behind ...
متن کاملHuman Coinfection with Borrelia burgdorferi and Babesia microti in the United States
Borrelia burgdorferi, the causative agent of Lyme disease, and Babesia microti, a causative agent of babesiosis, are increasingly implicated in the growing tick-borne disease burden in the northeastern United States. These pathogens are transmitted via the bite of an infected tick vector, Ixodes scapularis, which is capable of harboring and inoculating a host with multiple pathogens simultaneou...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Transfusion
سال: 2016
ISSN: 0041-1132,1537-2995
DOI: 10.1111/trf.13618